ASTM E1440-1991(2004) 短尾轮虫科剧毒性测试的标准指南
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【英文标准名称】:StandardGuideforAcuteToxicityTestwiththeRotiferBrachionus
【原文标准名称】:短尾轮虫科剧毒性测试的标准指南
【标准号】:ASTME1440-1991(2004)
【标准状态】:现行
【国别】:
【发布日期】:1991
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:E47.01
【标准类型】:(Guide)
【标准水平】:()
【中文主题词】:实验室医学;毒性;导则;试验
【英文主题词】:acutetoxicity;cysts;freshwater;invertebrate;LC50;marine;rotifers;toxicitytest
【摘要】:1.1Thisguidedescribesproceduresforobtaininglaboratorydataconcerningtheacutetoxicityofchemicalsandaqueouseffluentsreleasedintofresh,estuarine,ormarinewaters.AcutetoxicityismeasuredbyexposingBrachionusnewlyhatchedfromcyststoaseriesoftoxicantconcentrationsundercontrolledconditions.ThisguidedescribesatestforusingB.calyciflorus,afreshwaterrotifer,andtheAppendixdescribesmodificationsofthistestforestuarineandmarinewatersusingB.plicatilis.Theseproceduresleadtoanestimationofacutetoxicity,includingtheconcentrationexpectedtokill50%ofthetestrotifers(LC50)in24h.ProceduresnotspecificallystatedinthisguideshouldbeconductedinaccordancewithGuideE729andGuideE1192.1.2Modificationsoftheseproceduresmightbejustifiedbyspecialneedsorcircumstances.Althoughusingappropriateproceduresismoreimportantthanfollowingprescribedprocedures,theresultsoftestsconductedusingmodifiedproceduresmightnotbecomparabletorotiferacuteteststhatfollowtheprotocoldescribedhere.Comparisonoftheresultsusingmodifiedproceduresmightprovideusefulinformationconcerningnewconceptsandproceduresforconductingacutetoxicitytestsonchemicalsandaqueouseffluents.1.3Thisguideisorganizedasfollows:1.4Theseproceduresareapplicabletomostchemicals,eitherindividuallyorinformulations,commercialproducts,ormixtures.ThisguidecanalsobeusedtoconductinvestigationsoftheeffectsonrotifersurvivalofpH,hardness,andsalinityandonmaterialssuchasaqueouseffluents,leachates,oils,particulatematter,sediments,andsurfacewaters.Thisguidemightnotbeappropriateformaterialswithhighoxygendemand,withhighvolatility,subjecttorapidbiologicalorchemicaltransformation,orthatreadilysorbtotestchambers.1.5Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatorylimitationspriortouse.Forspecifichazardsstatements,seeSection.
【中国标准分类号】:C10
【国际标准分类号】:
【页数】:8P.;A4
【正文语种】:
【原文标准名称】:短尾轮虫科剧毒性测试的标准指南
【标准号】:ASTME1440-1991(2004)
【标准状态】:现行
【国别】:
【发布日期】:1991
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:E47.01
【标准类型】:(Guide)
【标准水平】:()
【中文主题词】:实验室医学;毒性;导则;试验
【英文主题词】:acutetoxicity;cysts;freshwater;invertebrate;LC50;marine;rotifers;toxicitytest
【摘要】:1.1Thisguidedescribesproceduresforobtaininglaboratorydataconcerningtheacutetoxicityofchemicalsandaqueouseffluentsreleasedintofresh,estuarine,ormarinewaters.AcutetoxicityismeasuredbyexposingBrachionusnewlyhatchedfromcyststoaseriesoftoxicantconcentrationsundercontrolledconditions.ThisguidedescribesatestforusingB.calyciflorus,afreshwaterrotifer,andtheAppendixdescribesmodificationsofthistestforestuarineandmarinewatersusingB.plicatilis.Theseproceduresleadtoanestimationofacutetoxicity,includingtheconcentrationexpectedtokill50%ofthetestrotifers(LC50)in24h.ProceduresnotspecificallystatedinthisguideshouldbeconductedinaccordancewithGuideE729andGuideE1192.1.2Modificationsoftheseproceduresmightbejustifiedbyspecialneedsorcircumstances.Althoughusingappropriateproceduresismoreimportantthanfollowingprescribedprocedures,theresultsoftestsconductedusingmodifiedproceduresmightnotbecomparabletorotiferacuteteststhatfollowtheprotocoldescribedhere.Comparisonoftheresultsusingmodifiedproceduresmightprovideusefulinformationconcerningnewconceptsandproceduresforconductingacutetoxicitytestsonchemicalsandaqueouseffluents.1.3Thisguideisorganizedasfollows:1.4Theseproceduresareapplicabletomostchemicals,eitherindividuallyorinformulations,commercialproducts,ormixtures.ThisguidecanalsobeusedtoconductinvestigationsoftheeffectsonrotifersurvivalofpH,hardness,andsalinityandonmaterialssuchasaqueouseffluents,leachates,oils,particulatematter,sediments,andsurfacewaters.Thisguidemightnotbeappropriateformaterialswithhighoxygendemand,withhighvolatility,subjecttorapidbiologicalorchemicaltransformation,orthatreadilysorbtotestchambers.1.5Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatorylimitationspriortouse.Forspecifichazardsstatements,seeSection.
【中国标准分类号】:C10
【国际标准分类号】:
【页数】:8P.;A4
【正文语种】:
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